What abnormal finding is associated with Marfan Syndrome regarding aortic diameter?

What abnormal finding is associated with Marfan Syndrome regarding aortic diameter?

• A. Aortic diameter >35 mm
• B. Aortic diameter >40 mm
• C. Aortic diameter >45 mm
• D. Aortic diameter >50 mm

Answer: (C)

In Marfan Syndrome, a connective tissue disorder, there is a well-documented association with aortic dilation and other cardiovascular abnormalities, particularly involving the aorta. The correct answer highlights that aortic diameter greater than 45 mm is considered a significant abnormal finding in individuals diagnosed with this syndrome. The rationale is based on the increased risk of aortic dissection and other cardiovascular complications that are notably higher in patients with aortic diameters exceeding this threshold. Monitoring and managing aortic size is essential in patients with Marfan Syndrome because the greater the diameter, the higher the risk of serious cardiovascular events, including rupture or dissection. While diameters greater than 35 mm, 40 mm, and 50 mm are of clinical interest, the specific threshold of 45 mm is critical for intervention and monitoring decisions in this population. This corresponds with guidelines that suggest surgical intervention may be necessary when the aortic diameter reaches this size, thereby helping physicians to better manage the associated risks in patients with Marfan Syndrome.

In Marfan Syndrome, a connective tissue disorder, there is a well-documented association with aortic dilation and other cardiovascular abnormalities, particularly involving the aorta. The correct answer highlights that aortic diameter greater than 45 mm is considered a significant abnormal finding in individuals diagnosed with this syndrome.

The rationale is based on the increased risk of aortic dissection and other cardiovascular complications that are notably higher in patients with aortic diameters exceeding this threshold. Monitoring and managing aortic size is essential in patients with Marfan Syndrome because the greater the diameter, the higher the risk of serious cardiovascular events, including rupture or dissection.

While diameters greater than 35 mm, 40 mm, and 50 mm are of clinical interest, the specific threshold of 45 mm is critical for intervention and monitoring decisions in this population. This corresponds with guidelines that suggest surgical intervention may be necessary when the aortic diameter reaches this size, thereby helping physicians to better manage the associated risks in patients with Marfan Syndrome.